Regulator Function and Stability Dynamics Intrinsic to Cystic Fibrosis Transmembrane Conductance Subject Collection Cystic Fibrosis The Cystic Fibrosis Airway Microbiome
نویسندگان
چکیده
Regulator (ABCC7) Structure Cystic Fibrosis Transmembrane Conductance John F. Hunt, Chi Wang and Robert C. Ford Perspective The Cystic Fibrosis Gene: A Molecular Genetic Lap-Chee Tsui and Ruslan Dorfman Cystic Fibrosis Status of Fluid and Electrolyte Absorption in M.M. Reddy and M. Jackson Stutts Anion Permeation The CFTR Ion Channel: Gating, Regulation, and Tzyh-Chang Hwang and Kevin L. Kirk Phenotypes The Influence of Genetics on Cystic Fibrosis Michael R. Knowles and Mitchell Drumm CFTR Assessing the Disease-Liability of Mutations in Claude Ferec and Garry R. Cutting Lessons from the Biochemical World −− Perspectives on Mucus Properties and Formation
منابع مشابه
A Review of The Role of The Microbiome on Immune Responses and Its Association With Cystic Fibrosis
In recent years, the microbiome has been recognized as a key regulator of immune responses. Evidence suggests that changes in the microbiome can lead to chronic disease and even exacerbation of the disease. Impairment of innate immunity resulting from microbial incompatibility may worsen host susceptibility to infection and exacerbate chronic lung diseases. Specific microbes play a key role in ...
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Cystic fibrosis (CF) is a life-limiting autosomal recessive disorder affecting principally respiratory and digestive system . It is caused by cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation. The aim of this study was to determine the extent of repeat numbers and the degree of heterozygosity for c.3499+200TA(7_56) and D7S523 located in intron 17b and 1 cM proximal to t...
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Cystic fibrosis is an autosomal recessive disease caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator protein. These mutations that correlate with different phenotypes, vary in their frequency and distribution in different populations. In this study missense mutation R117H that associated with the different clinical symptoms wa...
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A qualitative diagnosis of infertility requires attention to female and male physical abnormalities, endocrine anomalies and genetic conditions that interfere with reproduction. Many genes are likely to be involved in the complex process of reproduction. Cystic fibrosis (CF) incidence varies in different White people populations (a higher incidence of CF is observed in northern–western European...
متن کاملPrevalence of Cystic Fibrosis Trans-membrane Conductance Regulator Gene common mutations in children with cystic fibrosis in Isfahan, Iran
Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations. Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary ped...
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